Rh Phenotypes and Fisher's CDE Notation

1,2,3,6,7,8-Hexahydro­cinnolino[5,4,3-cde]cinnoline

The title compound, C(12)H(12)N(4), was synthesized by the reaction of hydrazine hydrate and 9-methyl-3,4,6,7-tetra-hydro-2H-xanthene-1,8(5H,9H)-dione in ethanol. In the crystal, the mol-ecule lies across an inversion centre. The pyridazine rings are coplanar and the C(6) rings adopt envelope conformations.

Modular Representation Theory and the CDE Triangle

Molecular analysis of Rh polypeptides in a family with RhD-positive and RhD-negative phenotypes.

To investigate the genetic basis of the Rh polypeptide gene, we attempted the isolation of cDNA clones for Rh polypeptide from a family with the RhD-positive and RhD-negative phenotypes using the reverse transcription (RT)-PCR method for each reticulocyte RNAs followed by subcloning. The isolated cDNAs showed the existence of another Rh-related clone (RhPII-1 cDNA, tentative designation) beside...

Antibody produced against isolated Rh(D) polypeptide reacts with other Rh-related antigens.

Rh(D) antigen-containing polypeptide was prepared by immune precipitation of intact cDE/cDE erythrocytes by using a high-titer preparation of polyclonal anti-D. when isolated Rh(D) polypeptide was administered to rabbits, antibody was produced that was unresponsive toward Rh-positive and -negative cells but reacted strongly with the immunogen in enzyme-linked immunosorbent assay-type immunobind...

From RTM-notation to ENP-score-notation

This paper discusses some recent developments within a compositional environment called PWGL. Our focus is to present how score information is represented in PWGL. We give some background information concerning the rhythmic notation that was used in PatchWork (a predecessor of PWGL). After this we show how this notation has been expanded so that it allows to generate very detailed scores that c...